The Synergic Effect of Erythrosine and Gold Nanoparticles in Photodynamic Inactivation

Photodynamic inactivation (PDI) is a process that uses photosensitizing substances to produce reactive oxygen species. This achieved by exposing photosensitizers specific wavelengths of light and causing oxidative damage in cells. sterilization technique commonly utilized has been extensively investigated owing its environmentally friendly inert characteristics. In this study, erythrosine was selected as the photosensitizer green light-emitting diode used source. Due their excellent biocompatibility, gold nanoparticles were added; these acted carrier for erythrosine, linking it Escherichia coli (E. coli) Colony-forming unit plate counting LIVE/DEAD bacterial viability tests performed. A synergic PDI effect photosensitizer, light, demonstrated. After irradiation 9 min, death rate higher than 97% achieved. Finally, study mechanism E. death, we conducted species adding different scavengers, concluded due production singlet (Type II reaction).